Cong, L., Ran, F.A., Cox, D. et al. Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819-823 (2013).

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The key results of the paper are as follows:

1. “Gene expression was upregulated by a factor of 3.2 in the treated cells.” Control mice showed no significant change in tumor dimensions over the same time period. (In Figure 4D.)
2. “The neural network achieved 96.5% accuracy on the test dataset.” The control group showed no significant change in expression levels. (In Figure 4C.)

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